Department of Otolaryngology
Zhang Zhigang
Doctor Title:chief physician
Department:Department of Otolaryngology
Political Status:Party Member of CPC
Overview

Current Position: The deputy director of the ENT department
Sun Yat-sen Memorial hospital
Yang Jiang Road 107, 510120, Guang Zhou, China
Email: zhangzhg@mail.sysu.edu.cn

Academic degrees
1992- 1995 Jiang Xi medical College Nan Chang, China
Master in Otorhinolaryngology

1982-1987 Heng Yang Medical College Heng Yang, China
Bachelor
Professional appointments:
Since 2014 Deputy director of the ENT department, Sun Yat-sen Memorial hospital
2009-2018 Head of Otology, Sun Yat-sen Memorial hospital

1995-2003 Deputy director of the ENT department, Guang Zhou Second people’s hospital

Selected publications
1. Zhang ZG, Liu X, Chen SJ, Chen B, Zheng YQ. Modification of closed tympanoplasty in middle ear cholesteatoma. Chinese Medical Journal. 2010,1;23(4):447-451
2. Zhang ZG, Liu X, Chen SJ, Zheng YQ.Combined tympanic epithelial layer avulsion and overlay myringoplasty for diffuse granular myringitis. The Journal of Laryngology & Otology. 2010,8;1-4
3. Zhang ZG, Zheng YQ, Chen SJ, Liu X, Chen B. Temporal Bone Histopathology Case of the Month Pediatric Malignant Peripheral Nerve Sheath Tumor in Auricula.Otology&neurotology.2010,9;31(7):1174
4. Zhang ZG, Chen SJ, Sun W, Chen B, Zheng YQ. Zhang Z G, Chen S J, Sun W, et al. Rare pediatric malignant peripheral nerve sheath tumor in auricula: A case report and literature review[J]. International Journal of Pediatric Otorhinolaryngology Extra, 2011, 6(2):59-61.
5. Zhang ZG, Chen SJ, Sun W, Zheng YQ.Classification and Surgical Management of Localized Attic Cholesteatoma:Single-Institution Experience and Follow-Up. ORL2010,2;72:96-100
6. Zhi Gang Zhang, Qiu Hong Huang, Yi Qing Zheng, Wei Sun,Yu Bin Chen, and Yu Si. Three Autologous Substitutes for Myringoplasty:A Comparative Study. Otology & Neurotology. 2011,32: 1234-1238.
7. Yu Si, Shao Chong Fan*, Zhi Gang Zhang*Osseointegration technique in patients with total acquired auricular deformities and failed previous reconstruction: a retrospective study of long term follow-up and Chinese experience. ORL,2012;74:129-135.
8. Si Y, Chen YB, Chen QX, Liu Y, Jiang HL, Zhang ZG. Autologous meatal skin graft implantation and intratympanic injection of Pseudomonas aeruginosa: a new experimental mouse model of acquired middle ear cholesteatoma[J]. ORL; journal for oto-rhino-laryngology and its related specialties, 2013, 75(5):274.
9. Chen Y, Chen S, Si Y, Liu Y, Xiong H, Zhang Z. Measurements of the position relationship between the inferior margin of the oval window and the endosteum of basal cochlear turn in histologic and HRCT study.[J]. Otology & neurotology: official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2013, 34(8):1528-1533.
10. Si Y, Zhang ZG, Chen SJ, Zheng YQ, Chen YB, Liu Y, Jiang H Feng LQ, Huang X. Attenuated TLRs in middle ear mucosa contributes to susceptibility of chronic suppurative otitis media[J]. Human Immunology, 2014, 75(8):771-776.
11. Liu Y, Chen Q, Si Y, Zhang ZG. Hodgkin's lymphoma of the temporal bone accompanied by intracranial abscess.[J]. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2014, 35(2):e95.
12. Si Y, Chen YB, Chen SJ, Zheng YQ, Liu X, Liu Y, Jiang HL, Xu G, Li ZH, Huang QH, Xiong H, Zhang ZG. TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction[J]. Scientific Reports, 2015, 5:16683.
13. Si Y, Chen Y, Li P, Jiang H, Xu G, Li Z, Zhang Z. Eardrum thickening approach for the treatment of patulous Eustachian tube[J]. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, 273(11):3673.
14. Jiang H, Si Y, Li Z, Huang X, Chen S, Zheng Y, Xu G, Chen X, Chen Y, Liu Y, Xiong H, Huang Q, Liang M, Zhang Z. TREM-2 promotes acquired cholesteatoma-induced bone destruction by modulating TLR4 signaling pathway and osteoclasts activation[J]. Scientific Reports, 2016, 6:38761.
15. ZHUO HAO LI#, YU SI#,GUO XU, XI MING CHEN,HAO XIONG,LAN LAI, YI QING ZHENG I, ZHI GANG ZHANG. High dose PMA plus RANKL and MCSF induce THP-1 into human functional osteoclast in vitro. Molecular Medicine Reports.2018.
16. Si Y, Chen Y, Li P, Jiang H, Xu G, Li Z, Zhang Z. Author's reply to a letter-to-the-editor about the paper 'Eardrum thickening approach for the treatment of patulous Eustachian tube'.[J]. European Archives of Oto-Rhino-Laryngology, 2017:1-2.
17. YuSi,Yu BinChen,Yu GuoChu,Sui JunChen,HaoXiong,Xi MingChen,Wu HuiHe,Yi QingZheng,Zhi GangZhang. Effects of combination of balloon Eustachian tuboplasty with methylprednisolone irrigation on treatment of chronic otitis media with Check for updates effusion in adults. AMERICAN JOURNAL OF OTOLARYNGOLOGY.2018.11
18. YuSi,Yubin Chen,Guo Xu,Ximing Chen,Wuhui He,Zhigang Zhang. Cartilage tympanoplasty combined with Eustachain tube ballon dilatation in the treatment of adhesive otitis media. The Laryngoscope.2018.09.
19. YuSi,Huai Li Jiang,Yu BinChen,Yu Guo Chu,Sui JunChen,Xi Ming Chen,Wu Hui He,Yi Qing Zheng,Zhi Gang Zhang. Round window niche drilling with intratympanic steroid is a salvage therapy of sudden hearing loss. Audiology and Neurotology,2018.08.