基础与转化医学研究中心
石中山
职称:副研究员
科室:基础与转化医学研究中心
概述
博士毕业于暨南大学,期间曾赴美国印第安纳大学医学院进行联合培养。主要研究方向为放射性脑损伤等神经疾病的机制与治疗,重点关注中枢及外周免疫的作用。以第一/通讯作者(含共同)在Neuron、CNS Neuroscience & Therapeutics等期刊发表SCI论文多篇,研究成果入选ESI高被引论文,被Nature Reviews Neuroscience 及Neuron杂志专题评述。主持国家自然科学基金青年项目、广东省自然科学基金面上项目、中国博士后科学基金站中特别资助及面上项目等。
代表性论文:
- Shi, Z.#, Yu, P.#, Lin, W. J.#, Chen, S.#, Hu, X, Chen, S, Cheng, J, Liu, Q, Yang, Y, Li, S, Zhang, Z, Xie, J, Jiang, J, He, B, Li, Y, Li, H, Xu, Y, Zeng, J, Huang, J, Mei, J, … Tang, Y*. Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes. Neuron, 2023, 111(5), 696–710.e9. (Featured by Nature reviews neuroscience and Neuron,Highly cited paper)
- Zhu, Y #, Cheng, J #, Li, Y #, Pan, D, Li, H, Xu, Y, Du, Z, Lei, M, Xiao, S*, Shen, Q*, Shi, Z*, & Tang, Y*. Progression of cognitive dysfunction in NPC survivors with radiation-induced brain necrosis: A prospective cohort. Radiology and Oncology, 2024, 190, 110033.
- Ma, X. #, Zuo, Y. #, Hu, X. #, Chen, S., Zhong, K., Xue, R., Gui, S., Liu, K., Li, S., Zhu, X., Yang, J., Deng, Z., Liu, X., Xu, Y., Liu, S., Shi, Z*, Zhou, M.*, & Tang, Y. *. Terminally differentiated cytotoxic CD4+ T cells were clonally expanded in the brain lesion of radiation-induced brain injury. CNS neuroscience & therapeutics, 2024, 30(3), e14682.
- Zhong, K#, Liu, K#, Song, Y#, Chen, S, Hu, X, Xue, R, Ma, X, Li, S, Yang, J, Deng, Z, Zhu, X, Yuan, M, Huang, Y, Yin, W, Chen, Y*, Tang, Y*, & Shi, Z*. A Synthetic Steroid 5α-Androst-3β, 5, 6β-triol Alleviates Radiation-Induced Brain Injury in Mice via Inhibiting GBP5/NF-κB/NLRP3 Signal Axis. Molecular neurobiology, 2023, DOI:10.1007/s12035-023-03831-9.
- Hu, X#, Li, S#, #, Lin, W. J, Yang, Y, Li, Y, Li, H, Xu, Y, Zhou, M*, & Tang, Y*. Partial Ablation of Astrocytes Exacerbates Cerebral Infiltration of Monocytes and Neuronal Loss After Brain Stab Injury in Mice. Cellular and molecular neurobiology, 2023, 43(2), 893–905.