基础与转化医学研究中心
鲍燕
职称:研究员
科室:基础与转化医学研究中心
概述

研究员,博士生导师。中山大学百人计划引进人才。主要研究方向是开发精准靶向裂解细胞膜的抗肿瘤及抗菌药物。在Nature Nanotechnology、Science Advances、PNAS等期刊发表论文。主持国家自然科学基金-青年科学基金项目和面上项目、广东省自然科学基金-杰出青年项目等。

 

  1. Mingdong Liu#, Liangqi Huang#, Weinan Zhang#, Xiaochuan Wang, Yuanyuan Geng, Yuhao Zhang, Li Wang, Wenbin Zhang, Yun-Jiao Zhang, Shiyan Xiao*, Yan Bao*, Menghua Xiong*, and Jun Wang*, A transistor-like pH-sensitive nanodetergent for selective cancer therapy, Nature Nanotechnology, 2022 May;17(5):541-551.影响因子34.9中科院SCI期刊大类分区:材料科学1ISSN: 1748-3387
  2. Yangbin Liang#, Yuhao Zhang#, Yu Huang#, Cheng Xu#, Jingxian Chen, Xinshuang Zhang, Bingchuan Huang, Zhanhui Gan, Xuehui Dong, Songyin Huang, Chengrun Li, Shuyi Jia, Pengfei Zhang, Yueling Yuan, Houbing Zhang, Yucai Wang, Bing Yuan, Yan Bao*, Shiyan Xiao*, Menghua Xiong*, Helicity-directed recognition of bacterial phospholipid via radially amphiphilic antimicrobial peptides, Science Advances, 2024 Aug 30;10(35):eadn9435. 影响因子12.5中科院SCI期刊大类分区:综合性期刊1ISSN: 2375-2548
  3. Xinshuang Zhang #, Dong Luo #, Jie Hu #, Kangxiu Wu, Shuyi Jia, Xueyi Li, Songyin Huang, Houbing Zhang, Dokyun Kim, Yuzhi Hong, Liping Zhao, Menghua Xiong*, and Yan Bao*, Selective Recognition of Bacterial Phospholipids by Antimicrobial Peptides: Employing a Host-Guest-Mediated Competitive Inhibition Strategy. Biomaterials. 2025 May 6:322:123392影响因子12.9,中科院SCI期刊大类分区:医学1区)ISSN: 0142-9612
  4. Xinshuang Zhang#, Shuyi Jia#, Xueyi Li#, Liping Zhao, Kangxiu Wu, Songyin Huang, Fan Zhang, Houbing Zhang, Dong Luo*, Menghua Xiong*, and Yan Bao*, Hydrophobicity-to-cationic amphipathicity transformable antimicrobial polypeptides for the prevention of medical implant-associated infections. Biomaterials. 2025 Jul 21:325:123564.影响因子12.9,中科院SCI期刊大类分区:医学1区) ISSN: 0142-9612
  5. Yang Bo, Yunjiang Jiang, Kangmei Chen, Kaimin Cai, Wenming Li, Jarron Roy, Yan Bao*, Jianjun Cheng*, Targeting infected host cells in vivo via responsive azido-sugar mediated metabolic cell labeling followed by click reaction, Biomaterials, 2020 April; 238:119843.影响因子12.9,中科院SCI期刊大类分区:医学1区) ISSN: 0142-9612
  6. Cuiyu Zhong#, Jie Li#, Suiping Liu, Weirong Li, Qiang Zhang, Junpeng Zhao, Menghua Xiong*, Yan Bao*, Yandan Yao*, Nanoblock-mediated selective oncolytic polypeptide therapy for triple-negative breast cancer, Theranostics, 2023; 13(9): 2800-2810. doi: 10.7150/thno.81834.(影响因子13.3,中科院SCI期刊大类分区:医学1区)ISSN: 1838-7640
  7. Weinan Zhang#, Xiaochuan Wang#, Jihong Wang#, Chanjuan Su, Yan Bao*, Menghua Xiong*, The relationship between in vivo toxicity and responsive pH in transistor-Like pH-sensitive nanodetergents, Small Methods, 2025 May;9(5):e2401263. (影响因子9.1,中科院SCI期刊大类分区:材料科学2区ISSN:2366-9608
  8. Yuhao Zhang, Yingxue Deng1, Chanjuan Su, Kangxiu Wu, Chengrun Li, Juntao Wang, Houbing Zhang, Dong Luo, Songyin Huang, Liping Zhao, Megnhua Xiong*, Yan Bao*, A conjugate strategy capable of targeting bacteria and selectively being activated at infection sites, Science China Materials, 2025 may 68(6):2132-2142影响因子7.4中科院SCI期刊大类分区材料科学1 ISSN: 2095-8226
  9. Yan Bao#, Xuewei Wu#, Jinjing Chen, Xiangming Hu, Fuxing Zeng, Jianjun Cheng, Hong Jin, Xin Lin, Lin-Feng Chen*, Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα, Proceedings of the National Academy of Sciences of the United States of America, 2017 May 16;114(20):E3993-E4001.(影响因子9.1,中科院SCI期刊大类分区:综合性期刊1区)ISSN: 0027-8424Faculty 1000推荐为2星论文
  10. Menghua Xiong#, Yan Bao#, Xin Xu#, Hua Wang, Zhiyuan Han, Zhiyu Wang, Yeqing Liu, Songyin Huang, Ziyuan Song, Jinjing Chen, Richard M. Peek Jr., Lichen Yin*, Lin-Feng Chen*, Jianjun Cheng*, Selective killing of Helicobacter pylori with pH-responsive helix-coil conformation transitionable antimicrobial polypeptides, Proceedings of the National Academy of Sciences of the United States of America, 2017 Nov 28;114(48):12675-12680.(影响因子9.1,中科院SCI期刊大类分区:综合性期刊1区)ISSN: 0027-8424