基础与转化医学研究中心
廖建友
职称:研究员
科室:基础与转化医学研究中心
政治面貌:中国共产党党员
概述
个人简介:
廖建友,博士,研究员,博士生导师,智慧医学中心主任,医学研究教职工党支部书记,深汕院区精准医学中心主任。入选人才计划:广东省杰出青年科学基金、广东省“特支计划”科技创新青年拔尖人才、广州市“珠江科技新星”人才培养计划、中山大学孙逸仙纪念医院医学科学家-学术骨干、中山大学孙逸仙纪念医院“逸仙优秀青年医学人才”培养计划。主要从事AI驱动的精准医学和RNA调控乳腺癌发生发展机制研究。到目前为止以第一或者通讯作者的身份发表SCI收录论文17篇,包括Cell(IF:45.5)、Nature Communications(14.7,2篇)、PNAS(IF:10.0)、Nucleic Acids Research(IF:16.6,3篇)、Genome Biology(IF:10.1,封面文章)等高水平专业杂志,以共同作者身份在国际顶级杂志Nature(IF:64.8)、Cell(IF:45.5)、Nature Biotechnology(IF:64.5)等发表16篇研究论文。本人研究受到了15项省部级以上精准医学相关基金资助,包括5项国家自然科学基金。目前主要研究方向有:(1)AI驱动的精准医学;(2)RNA医学;(3)生物信息学。
联系方式:liaojy3@mail.sysu.edu.cn
发表论文:
- Z. Z. Yang#, B. Yang#, H. Yan#, X. Ma#, B. Tian, B. Zheng, Y. X. Chen, Y. M. Dong, J. Deng, Z. Zhan, Y. Shi, J. Y. Zhang, D. Lu, J. H. He, Y. Zhang, K. Hu, S. Zhu, K. Zhou, Y. C. Zhang, Y. Zheng*, D. Yin*, J. Y. Liao*, DCAF13-mediated K63-linked ubiquitination of RNA polymerase I promotes uncontrolled proliferation in Breast Cancer, Nat Commun 16(1) (2025) 557. (IF:14.9)
- Y Shi#, Q Pan#, W Chen#, L. Xie, S. Tang, Z. Yang, M. Zhang, D. Yin, L. Lin* and J. Y. Liao*, Pan-Cancer Oncogenic Properties and Therapeutic Potential of SF3B4, Cancer Gene Therapy (2025) (IF:4.8)
- Y Lu*, Q Zhao*, J. Y. Liao*(共同第一), E Song, Q Xia, J Pan, Y Li, J Li, B Zhou, Y Ye, C Di, S Yu, Y Zeng, S Su # Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity, Cell (2020), 180, 1–17(IF:64.5)
- J. Y. Liao*#, B. Yang#, C. P. Shi#, W. X. Deng, J. S. Deng, M. F. Cen, B. Q. Zheng, Z. L. Zhan, Q. L. Liang, J. E. Wang, S. Tao, D. Lu, M. Liang*, Y. C. Zhang*, D. Yin*, RBPWorld for exploring functions and disease associations of RNA-binding proteins across species, Nucleic Acids Res 53(D1) (2025) D220-D232.(IF:16.6)
- J. Y., Liao, *# (共同通讯), B., Yang*,Y. C., Zhang*, D. C., Lin#, D., Yin#, EuRBPDB: a comprehensive resource for annotation, functional and oncological investigation of eukaryotic RNA binding proteins (RBPs). Nucleic Acids Res (2019) , gkz823. (IF:11.147)
- J. Y., Liao, Y. H. Guo, L. L. Zheng, Y. Li, W. L. Xu, Y. C. Zhang, H. Zhou, Z. R. Lun, F. J. Ayala and L. H. Qu (2014). "Both endo-siRNAs and tRNA-derived small RNAs are involved in the differentiation of primitive eukaryote Giardia lamblia." Proc Natl Acad Sci U S A 111(39): 14159-14164.(IF:11.1)
- Yang B#, Zhang M#, Shi YM#, Zhang BQ#, J.Y. Liao*(共同通讯),Dong Y* PerturbDB for unraveling gene functions and regulatory networks, Nucleic Acids Res, 2024, (IF:16.6)
- Liu X, Ye Y, Zhu L, Xiao X, Zhou B, Gu Y, Si H, Liang H, Liu M, Li J, Jiang Q, Li J, Yu S, Ma R, Su S, J. Y., Liao*(共同通讯), Zhao Q: Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation. Nat Commun 2023, 14:238.(IF:14.9)
- Zhang, Y. C.*, J. Y., Liao*(共同第一), Z. Y. Li, Y. Yu, J. P. Zhang, Q. F. Li, L. H. Qu, W. S. Shu and Y. Q. Chen (2014). "Genome-wide screening and functional analysis identify a large number of long noncoding RNAs involved in the sexual reproduction of rice." Genome Biol 15(12): 512.(封面文章)(IF:12.3,引用533次)
- J. Y. Liao, J. Wu, Y. J. Wang, J. H. He, W. X. Deng, K. Hu, Y. C. Zhang, Y. Zhang, H. Yan, D. L. Wang, Q. Liu, M. S. Zeng, H. Phillip Koeffler, E. Song and D. Yin (2017). "Deep sequencing reveals a global reprogramming of lncRNA transcriptome during EMT." Biochim Biophys Acta 1864(10): 1703-1713. (IF:5.1)