基础与转化医学研究中心
朱亚锋
职称:副研究员
科室:基础与转化医学研究中心
概述

  中山大学“百人计划”引进人才,广东省优粤人才B类。瑞典卡罗林斯卡医学院博士,美国哈佛医学院博士后,2020年8月全职回国。研究方向为肿瘤蛋白质组学,研究内容包括:1)非编码区序列翻译产物鉴定和功能研究;2)单细胞-空间蛋白质组学技术解析肿瘤异质性及抗药机制;3)化学蛋白质学解析药物作用机制。研究成果发表于Nature Communications, Nucleic Acids Research等国际知名期刊,共计发表SCI论文15篇,,高引指数(H-index)11, 他引共计900余次。

联系方式:yafeng.zhu@outlook.com

代表性论文:

1. Rong Xiang, Leyao Ma, Mingyu Yang, Zetian Zheng, XiaoFang Cheng, Fujian Jia, Fanfan Xie, Fuqiang Li, Kui Wu, Yafeng Zhu*. Increased expression of peptides from non-coding genes in cancer proteomics datasets suggests potential tumor neoantigens. Communications Biology. April 2021. Impact factor: 6.3 中科院JCR生物学1区

2. Yafeng Zhu*,Lukas Örre*, Yan Tran, Georgios Mermelekas, Henrik J. Johansson, AlinaMalyutina, Simon Anders, Janne Lehtiö. DEqMS: a method for accurate proteinvariance estimation in differential proteomics analysis. Molecular &Cellular Proteomics. 2020 April. Impact factor: 6.1 中科院JCR生物学2区

3. Yafeng Zhu, Lukas Orre, Henrik Johansson, Mikael Huss, Jorrit Boekel, Mattias Vesterlund, Alejandro Fernandez-Woodbridge, Rui M. M. Branca* & Janne Lehtiö*.Discovery of coding regions in human genome by integrated proteogenomics analysis workflow. Nature Communications. March 2018. Impact factor: 14.7. 中科院JCR综合性期刊1区

4. Yafeng Zhu*,Pär G Engström*, Christian Tellgren-Roth, Charles Baudo, John C Kennell, ShengSun, R. Blake Billmyre, Markus S. Schröder, Anna Andersson, Tina Holm, BenjaminSigurgeirsson, Guangxi Wu, Sundar Ram Sankaranarayanan, Rahul Siddharthan,Kaustuv Sanyal, Joakim Lundeberg, Björn Nystedt, Teun Boekhout, Thomas L DawsonJr., Joseph Heitman, Annika Scheynius*, Janne Lehtiö*. Proteogenomics producescomprehensive and highly accurate protein-coding gene annotation in a completegenome assembly of Malassezia sympodialis. Nucleic Acids Research, Jan 2017.Impact factor: 16.6 中科院JCR生物学2区

5. Yafeng Zhu,Lina Hultin-Rosenberg, Jenny Forshed, Rui M. M. Branca, Lukas M. Orre, andJanne Lehtiö.  SpliceVista, a tool forsplice variant identification and visualization in shotgun proteomics data. Molecular & Cellular Proteomics. 2014 Jun. Impact factor: 6.1 中科院JCR生物学2区

6. Pierre Montay-Gruel#, Yafeng Zhu#, Petit Benoit, Ron Leavitt, Mike Warn, Erich Giedzinski, Jonathan Ollivier, David A. Sinclair, Marie-Catherine Vozenin* and Charles L. Limoli* Extracellular vesicles for the treatment of radiation-induced normal tissue toxicity in the lung.. . Frontiers in Oncology. March 2021. Impact factor: 3.5 中科院JCR医学3区

7. Haidi Yang#, Yafeng Zhu#, Yongyi Ye#, Jiao Guan, Xin Min, Hao Xiong. Nitric oxide protects against cochlear hair cell damage and noise-induced hearing loss through glucose metabolic reprogramming. Free Radical Biology and Medicine. Volume 179, 1 February 2022. Impact factor: 7.1 中科院JCR生物学2区

 

8. PernemalmM§, Sandberg A§, Zhu Y, Boekel J, Tamburro D, Schwenk J M, Björk A,Wahren-erlenius, M, Åmark H, Östenson C.G, Westgren M, Lehtiö J*. In-depthhuman plasma proteome analysis captures tissue proteins and transfer of proteinvariants across the placenta. eLife. May 2019. Impact factor: 6.4 中科院JCR生物1区

9. HenrikJ. Johansson, Fabio Socciarelli, Nathaniel Vacanti, Mads H. Haugen, Yafeng Zhu, Ioannis Siavelis, Alejandro Fernandez, Miriam R. Aure, Bengt Sennblad,Mattias Vesterlund, Rui M. Branca, Lukas Orre, Mikael Huss, Erik Fredlund, ElsaBeraki, Øystein Garred, Jorrit Boekel, Torill Sauer, Wei Zhao, Silje Nord, ElenK. Höglander, Tonje H. Haukaas, Tone F. Bathen, Ellen Schlichting, Bjørn Naume,OSBREAC, Elin Borgen, Vessela N. Kristensen, Hege EG. Russnes, Ole ChristianLingjærde, Gordon B. Mills, Kristine K. Sahlberg, Anne-Lise Børresen-Dale,Janne Lehtiö. Breast cancer quantitative proteome and proteogenomic landscape. Nature communication. April 2019. Impact factor: 14.7. 中科院JCR综合性期刊1区

10. LukasMinus Orre*, Mattias Vesterlund*, Yanbo Pan*, Taner Arslan*, Yafeng Zhu,Alejandro Fernandez Woodbridge, Oliver Frings, Erik Fredlund and Janne Lehtiö. SubCellBarcode: Proteome-wide mapping of protein localization and relocalization. Molecular Cell. January 2019. Impact factor: 14.50 中科院JCR生物1区

11. GiovanniNassa, Giorgio Giurato, Giovanni Cimmino, Francesca Rizzo, Maria Ravo,Annamaria Salvati, Tuula Nyman, Yafeng Zhu, Mattias Vesterlund, JanneLehtiö, Paolo Golino, Alessandro Weisz, and Roberta Tarallo. Splicing ofplatelet resident pre-mRNAs upon activation by physiological stimuli results infunctionally relevant proteome modifications. Sci. Rep. Jan 2018. Impact factor: 4.13. 中科院JCR综合性期刊3区