Prof. Lin Tianxin's Team Won the First Prize of the Guangdong Medical Science and Technology Award
On the afternoon of January 13, 2022, Prof. Lin Tianxin’s team was conferred with the First Prize for the project “Establishment, Promotion and Application of Precise Diagnosis and Treatment System for Bladder Cancer” at the Third Guangdong Medical Science and Technology Award Ceremony held in Guangzhou. The Guangdong Medical Science and Technology Award aims to support the development of medical science and technology for encouraging the innovation of medical talents and driving the translation of medical science and technology achievements. This prestigious award is a recognition of the work achieved by the urology team at Sun Yat-sen Memorial hospital, Sun Yat-sen University.
Lin Tianxin (the first one from the right), vice president of Sun Yat-sen Memorial Hospital, SYSU, and the principle leader for the project “Establishment, Promotion and Application of Precise Diagnosis and Treatment System for Bladder Cancer”, was conferred with the First Prize of Guangdong Medical Science and Technology Award.
Participants of the awarded project include: Lin Tianxin, Huang Jian, Chen Xu, He Wang, Wu Shaoxu, Chen Changhao, Wang Bo, Zheng Junjiong, Xie Ruihui, Liu Hao, Li Kaiwen, Yu Hao, Zhong Wenlong
Project Introduction
Bladder cancer is one of the most common malignant tumors of the urinary system in China. With high incidence and recurrence rate, it is prone to lymphatic metastasis and insensitive to chemotherapy. Clinically, there are a number of problems relating to inaccurate diagnosis and treatment of bladder cancer, including the lack of effective non-invasive diagnostic techniques, inaccurate preoperative staging diagnosis, large trauma in open surgery, and lack of treatment methods for lymphatic metastasis and chemotherapy resistance. Therefor, it is of great scientific and clinical value to carry out research on precise diagnosis and treatment of bladder cancer.
Since 2008, the team of Prof. Lin Tianxin and Prof. Huang Jian from Sun Yat-sen Memorial Hospital, Sun Yat-sen University, have achieved the following breakthroughs with the support of multiple national research projects:
- Develop a new technology for non-invasive diagnosis of bladder cancer by examining urine sample; establish a method for immune prognosis classification of bladder cancer; achieve non-invasive diagnosis and prognosis prediction of bladder cancer; and provide a scientific support for accurate diagnosis and treatment of bladder cancer.
- Develop a precision diagnosis approach for lymphatic metastasis of bladder cancer, which is the first in the world; propose a new CT/MRI diagnostic standard for pelvic lymphatic metastasis of bladder cancer; develop lymphatic metastasis prediction methods based on CT, MR and gene expression; improve the accuracy of preoperative lymphatic staging , and guide the precise surgical resection range.
- Take the lead in establishing standardized laparoscopic radical cystectomy, and confirm that the efficacy of laparoscopic surgery for tumor root treatment is comparable to that of open surgery, with less trauma, bleeding and complications, and has advantages in preserving urinary continence and sexual function. Modify Laparoscopic Surgery for women, and establish a rapid postoperative recovery plan to promote the popularization and application of minimally invasive surgery for bladder cancer in China.
- Be the first to elucidate the key mechanism of lymphatic metastasis of bladder cancer, discover new therapeutic targets for blocking lymphatic metastasis, and fill the research gap of lymphatic metastasis in China. Reveal the regulatory mechanism of chemotherapy resistance in bladder cancer, identify chemosensitivity predictive markers and propose new strategies for sensitization.
Relevant research results have been published in internationally renowned journals such as Eur Urol, J Clin Invest, Nat Commun, Clin Cancer Res, etc. Among them, 16 papers have IF >10 points, and 5 papers have been selected as ESI high Cited Papers. The above-mentioned research results have been included in the Guidelines for Diagnosis and Treatment of Bladder Cancer in China, which are widely used in China and have changed the diagnosis and treatment mode of bladder cancer in our country. Relying on the South China Minimally Invasive Technology Training Center and the China Bladder Cancer Alliance, the team has promoted and applied the bladder cancer precise diagnosis and treatment technology system in more than 200 hospitals from over 30 provinces and cities in China, which has significantly improved the quality of life and survival rate of bladder cancer patients, and achieved good results in social and economic benefits.
About Guangdong Medical Science and Technology Award
In order to encourage the development and innovation of medical science and technology in Guangdong Province, and to award units and individuals who have made outstanding contributions to the progress of medical science and technology, the Guangdong Medical Association has established the Guangdong Medical Science and Technology Award to further promote innovative research in medical science and new technology development. The award ceremony has been held for three consecutive years.
This year's Guangdong Medical Science and Technology Award has a total of 140 application projects. After strict procedures of selection, 36 award-winning projects have been selected, including 34 medical science and technology awards first prizes, 14 second prizes, 12 third prizes, and 2 science popularization prizes.
Professor Lin Tianxin
Doctoral Supervisor
Vice President of Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Secretary General and Standing Committee Member, the Urology Branch of Chinese Medical Association
Vice President, the Urology Branch of Chinese Medical Doctor Association
Chair, the Urology Branch of Guangdong Medical Association
Member of the Standing Committee, the Robot Doctor Branch of the Chinese Medical Doctor Association
Chief Scientist of National Key R&D Program
Recipient of the National Science Fund for Distinguished Young Scholars
About the Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University:
National Key Clinical Specialty
Guangdong Provincial Key Clinical Specialty
High-level Clinical Key Specialty of Guangdong Province
One of the most influential departments in the field of urology in China (No. 1 in South China, No. 4 in China)
Guangdong Urology Medical Quality Control Center
Guangdong Urinary System Disease Clinical Medical Research Center
Chinese Medical Association Urology Branch (CUA) Continuing Education and Training Center
Societe Internationaled' Urologie (SIU) Accredited Training Center
Original Article: http://www.gzsys.org.cn/article/18693
