张寅，副研究员，硕士生导师。从事RNA蛋白相互作用、基因组和表观调控在肿瘤中功能和机制研究。到目前为止以第一或者通讯作者的身份发表SCI收录论文16篇。包括Nucleic Acids Research、Cancer Research、Autophagy、Theranostics、Journal of Nanobiotechnology等等高水平专业杂志。本人研究受到了3项国家和省部级基金资助。目前本人兴趣点主要在利用生物信息和人工智在表观组、基因组和转录组层面发掘肿瘤调控的新机制，同时我们还开发建立了一系列原创的方法和工具，从新的角度揭示肿瘤的发生发展和耐药的深层分子机制和临床意义。

联系方式：zhangy525@mail.sysu.edu.cn

代表性文章：

1. Yun Li#, Hengxing Chen#, Xuan Xie#, Bing Yang, Xiaojuan Wang, Jingyuan Zhang, Tian Qiao, Jiao Guan, Yuntan Qiu, Yong-Xin Huang, Duanqing Tian, Xinyi Yao, Daning Lu, H Phillip Koeffler，Yin Zhang*(共同通讯), Dong Yin*， PINK1-Mediated Mitophagy Promotes Oxidative Phosphorylation and Redox Homeostasis to Induce Drug-Tolerant Persister Cancer Cells, Cancer Research, 2023 Feb 3;83(3):398-413

2. Ying Liu#, Guangwei Ma#, Zenghong Gao, Jian Li, Jin Wang, Xiangping Zhu, Ruowu Ma, Jiawen Yang, Yiting Zhou, Kaishun Hu, Yin Zhang*(共同通讯), Yabin Guo*, Global chromosome rearrangement induced by CRISPR-Cas9 reshapes the genome and transcriptome of human cells, Nucleic Acids Research, 2022;50(6):3456-3474

3. Yun Li#, Hengxing Chen#, Daning Lu, H Phillip Koeffler, Yin Zhang*(共同通讯), Dong Yin*, Mitophagy is a novel protective mechanism for drug-tolerant persister (DTP) cancer cells, Autophagy, 2023 Feb 15;1-2

3. Yin Zhang#（第一作者）, Yong-xin Huang#, Dan-lan Wang, Bing Yang, Hai-yan Yan, Le-hang Lin, Yun Li, Jie Chen, Li-min Xie, Yong-sheng Huang, Jian-you Liao, Kai-shun Hu, Jie-hua He, Phei Er Saw, Xiao-ding Xu, Dong Yin*, LncRNA DSCAM-AS1 interacts with YBX1 to promote cancer progression by forming a positive feedback loop that activates FOXA1 transcription network, Theranostics, 2020; 10(23): 10823-10837 

4. Yin Zhang#（第一作者）, Yong-Xin Huang#, Xin Jin#, Jie Chen, Li Peng, Dan-Lan Wang, Yun Li, Xin-Yi Yao, Jian-You Liao, Jie-Hua He, KaiShun Hu, Daning Lu, Yabin Guo*, Dong Yin*, Overexpression of lncRNAs with endogenous lengths and functions using a lncRNA delivery system based on transposon, Journal of Nanobiotechnology, 2021 Oct,19(1):303

6. Yin Zhang#（第一作者）, Ye-Ya Tan #, Pei-Pei Chen #, Hui Xu, Shu-Juan Xie, Shi-Jun Xu, Bin Li, Jun-Hao Li, Shun Liu, Jian-Hua Yang, Hui Zhou, Liang-Hu Qu*. Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development, Cell Death and Disease, 2021 Dec 14; 12(12):1161

7. Zixian Huang#, Yin Zhang#（共同一作）, Haigang Li, Yufeng Zhou, Qianyu Zhang, Rui Chen, Tingting Jin, Kaishun Hu, Shihao Li, Yan Wang, Weiliang Chen*, Zhiquan Huang*, Vitamin D promotes the cisplatin sensitivity of oral squamous cell carcinoma by inhibiting LCN2-modulated NF-κB pathway activation through RPS3, Cell Death and Disease, 2019 Dec 9;10(12):936

8. Ye-Ya Tan#, Yin Zhang#（共同一作）, Bin Li, Yang-Wen Ou, Shu-Juan Xie, Pei-Pei Chen, Shi-Qiang Mei, Qiao-Juan Huang, Ling-Ling Zheng, Liang-Hu Qu*, PERK Signaling Controls Myoblast Differentiation by Regulating MicroRNA Networks, Frontiers in Cell and Developmental Biology, 2021 May 28;9:670435

9. Qianyu Zhang#, Zixian Huang#, Xi Rui#, Yan Wang#, Yongqiang Wang, Yuwei Zhou, Rui Chen, Yongju Chen, Yuepeng Wang, Shihao Li, Haigang Li, Ximing Shen, Yancan Liang, Yin Zhang*(共同通讯), Zhiquan Huang*, GSDMD enhances cisplatin-induced apoptosis by promoting the phosphorylation of eIF2α and activating the ER-stress response, Cell Death Discovery, (2022) 8:114